People at risk for heart disease are much more likely to die from a
stroke if they don't take cholesterol-lowering statin drugs and blood
pressure medications as prescribed, a new study reports.
Folks with high blood pressure and high cholesterol had a seven times
greater risk of suffering a fatal stroke if they didn't follow their
drug regimen to lower cholesterol and blood pressure.
The study findings were published online March 28 in the Journal of the American College of Cardiology.
Fatal stroke risk also increased if these patients stuck to one type of medication but not both, the researchers found.
For example, if patients kept taking blood pressure medication but
dropped their statins, their risk of dying from a stroke increased by 82
percent. Turning the tables, they had a 30 percent added risk of stroke
if they took their statins but didn't take their blood pressure
medications.
"High blood pressure and high cholesterol concentration are key risk
factors for stroke for which effective medication is available," said
study lead author Kimmo Herttua, head researcher for the Center of
Maritime Health and Society at the University of Southern Denmark. "A
major obstacle for the full benefits of lipid-lowering and
antihypertensive treatments is the non-adherence of patients to drug
therapy."
Stroke is responsible for 12 percent of all deaths worldwide, and it
is the second leading cause of death after heart disease, the
researchers said.
In this study, Herttua and colleagues tracked data on more than
58,000 patients in Finland with high cholesterol levels. During an
average 5.5 years of follow-up, 532 died of stroke.
The researchers used prescription records to track whether people
were taking medications as their doctors ordered. They found that only
six out of 10 people took statins as prescribed.
Experts cited a number of reasons patients might find it tough to keep up with all their medications.
Doctors struggle to get patients to stick to any sort of
health-improving regimen, noted Dr. Nieca Goldberg, a cardiologist and
medical director of NYU Langone's Joan H. Tisch Center for Women's
Health.
"One of the challenges in taking care of patients is getting them to
start a program and get them to continue it, whether it's getting them
to exercise, cut down on their sugar intake or take their medicine," she
said.
Doctors may not be properly explaining the role of these drugs in
their health, and the necessity of taking them as prescribed, Goldberg
and Herttua said.
"People need to understand the connection between taking those
medicines and preventing a heart attack or stroke," Goldberg said.
"Face-to-face time being limited in the doctor's office, that is kind of
getting lost in the visit."source-healthnews
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